W. Allan King

(BSc, MSc Guelph, PhD Uppsala | Professor | Tier 1 Canada Research Chair - Animal Reproductive Biotechnology)



Contact Information

Extension: 54927 | Email: waking@uoguelph.ca

Areas of Interest

  • Cytogenetic and morphologic aspects of fertilization and early development
  • In vitro fertilization, embryo culture and cloning
  • Gene expression in embryos
  • Sex chromosome linked gene expression

Current Graduate Students

Arshia Azizeddin, B.Sc.H. (Guelph)
- MBS candidate

Fazl Ashkar, M.D. (Iran)
Role of mitochondria in oocyte and early development. Effect of thyroid hormones on mitochondria in oocyte and early development.
- Ph.D. candidate

Tim Carter, B.Sc.H. (Guelph)
Telomere dynamics in aging and developing cellular populations.
- Ph.D. candidate

Jeff Caudle, B.Sc. (Guelph)
Expression of Y chromosome linked genes in bovine pre-implantation embryos.
- M.Sc. candidate

Jackie Ferris, B.Sc., BPHE (Queen's), M.Sc. (Guelph)
- Ph.D. candidate

Graham Gilchrist, B.Sc. (Guelph)
Bovine sex specific telomere analysis.
- Ph.D. candidate

Leslie Gonzalez Grajales
- Ph.D. candidate

Olutobi Oluwole, D.V.M., M.Sc. (Ibadan), M.Sc. (Guelph)
- Ph.D. candidate

Kayla Perkel, B.Sc.H. (Guelph)
Non-invassive assessment of embryo viability in bovine embryos.
- Ph.D. candidate

Robyn Pimm, B.Sc.H. (Guelph)
Manipulation of the reproductive cycle in veiled chameleons.
- M.Sc. candidate

Tuyet Ahn Quach, DVM (Vietnam), M.Sc. (Guelph)
Assessment of hypoprolific boars for chromosome abnormalities and copy number variations including genes in the male-specific region of the Y chromosome.
- Ph.D. candidate

Na-Young Rho, B.Sc.H. (Korea)
- M.Sc. candidate

Stewart Russell, B.Sc.H. (WLU)
- MBS candidate

Sylvia Santos, B.Sc.H. (Guelph)
- MBS candidate

Laura Schep, B.A.S. (Guelph)
- MBS candidate

Natasha Smith, B.Sc. (Guelph)
- MBS candidate

Anja Stojsin, B.Sc. (Guelph), M.Sc. (Sweden)
- Ph.D. candidate

 

Reham Abdelaal, B.Sc.H. (Guelph)
The effect of hydrogen peroxide on bovine fibroblast culture cells: investigating its potential role in apoptosis and necrosis.
- MBS candidate - GRADUATED S'11

Catherine Barrington, B.Sc.H. (Guelph)
Investigating the effect of cortisol on bovine embryo development.
M.Sc. candidate - GRADUATED S'09

John Beduhn, B.Sc. (Hamilton)
Chronology of X-chromosome inactivation in bovine embryos produced by IVF and SCNT.
- M.Sc. candidate - GRADUATED F'08

Lindsay Di Paolo, B.Sc. (London)
Interests: in vitro fertilization, pre-implantation embryo development
- M.Sc. candidate - GRADUATED S'09

Alexandra Durno, B.Sc. (Guelph)
Influence of stress on reproductive function in Vancouver island marmots. Hormone cycling patterns and metabolite excretion in reproductively successful female marmots.
- M.Sc. candidate - GRADUATED F'08

Katanya Fuerst, B.Sc. (Guelph)
Superovulation of ewes via the use of gonadotrophins, in particular the role FHS plays in follicular wave development.
- M.Sc. candidate - GRADUATED F'08

Christine Hamilton, B.Sc. (Guelph)
Copy number variation of testis-specific protein Y-encoded (TSPY) in cattle and its phenotypic implications in cattle.
- Ph.D. candidate - GRADUATED W'11

Ezra Hart, B.Sc. (Guelph)
Interests: cytogenetics, reproduction, cloning, cattle
- M.Sc. Candidate - GRADUATED W'09

Andrea Hunt, B.Sc. (Guelph)
Oxidative stress and its role in premature cell senescence.
- M.Sc. candidate - GRADUATED S'11

Angus MacAulay, B.Sc. (Guelph)
Steroid hormones and their influence on the sex ratio of in-vitro produced bovine embryos.
- M.Sc. candidate - GRADUATED S'10

Sandra MacTavish, B.Sc.H. (Western)
Ethanol Evaporation upon Incubation in Relation to Ethanol Treatment during Bovine in vitro Maturation.
- MBS candidate - GRADUATED S'11

Alexandra McClenahan, B.Sc.H. (Guelph)
The sex ratio of in vitro produced arrested bovine embryos (Bos taurus).
- MBS candidate - GRADUATED S'11

Lisa Milligan, B.Sc. (Waterloo)
RNA binding protein expression during early embryonic development.
- MBS candidate - GRADUATED S'11

Katie Morin, B.Sc. (Guelph)
Assessing developmental potential of bison embryos in vitro.
- M.Sc. candidate - GRADUATED F'08

Tuyet Anh Quach, DVM (Vietnam)
Identification of chromosome abnormalities in boars with reduced litter size.
- M.Sc. candidate - GRADUATED F'08

Peter Seaby, B.Sc. (Guelph)
Investigating the influences of mitochondrial gene expression on the development of in vitro produced pure and hybrid bison embryos.
- M.Sc. candidate - GRADUATED S'10

Raji Sextus, B.Sc. (York)
RNA binding protein expression during early embryonic development.
- M.Sc. candidate - GRADUATED S'10

Eduardo Sosa, B.Sc. (Mexico)
Epigenetic reprogramming during early embryonic development. Demethylation patterns in IVF and SCNT derived embryos.
- Ph.D. candidate - GRADUATED S'11

Adrian Stacy, B.Sc.H. (McMaster)
miRNAs in the bovine oocyte and early embryo.
- MBS candidate - GRADUATED S'11

Sonja Swanson, B.Sc.H. (Guelph)
Sex Ratio and Rates of Apoptosis in Bovine Embryos Following Androgen Treatment.
- MBS candidate - GRADUATED S'11

Emily Van de Laar, B.Sc. (Guelph)
- M.Sc. candidate - GRADUATED F'09

Selected References

  • Ashkar FA, Semple E, Schmidt C, St John E, Bartlewski PM, King WA. (2010) Thyroid hormone supplementation improves bovine embryo development in vitro. Human Reproduction. 25:334-344.
  • Quach TA, Villagomez DAF, Coppola G, Pinton A, Hart EJ, Reyes RE, Basrur PK, King WA (2009)  A cytogenetic study of breeding boars in Canada. Cytogenetics and Genome Research 126: 271-280.
  • Villagomez DAF, Parma P , Radi O , Di Meo G , Pinton A , Iannuzzi L, King WA (2009)  Classical and molecular cytogenetics in domestic animals affected by anomalies involving sex determination and/or differentiation . Cytogenetics and Genome Research 126: 110-131.
  • Dos Santos Miranda M, Bressan FF, Zecchin KG, Vercesi AE, Mesquita LG, Fonseca Merighe GK, King WA, Ohashi OM, Pimentel JR, Perecin F, Meirelles FV. (2009) Serum-Starved Apoptotic Fibroblasts Reduce Blastocyst Production but Enable Development to Term after SCNT in Cattle. Cloning Stem Cells. 11: 565-573.
  • Hamilton CK, Favetta LA, Di Meo GP, Floriot S, Perucatt A, Pieppo J, Kantanen J, Eggan A, Iannuzzi  L, King WA. (2009) Copy number variation of tesis-specific protein, Y encoded (TSPY) in fourteen different breeds of cattle (Bos taurus). Sexual Development 3: 205-13.
  • Blondin P, Beaulieu M, Fournier V, Morin N, Crawford L, Madan P, King WA. (2009) Analysis of bovine sexed sperm for IVF from sorting to the embryo., Theriogenology. 71(1):30-8
  • Jeon B-G, Coppola G, Perrault SD, Rho G-J, Betts DH, King WA (2008) S-adenosyl-homocysteine treatment of adult female fibroblasts alters X chromosome inactivation and improves in vitro embryo development after somatic cell nuclear transfer. Reproduction 135:815-28
  • Coppola G, Pinton A, Joudrey EM, Basrur PK, King WA (2008) Spatial distribution of histone isoforms on the bovine active and inactive x chromosome. Sexual Development 2: 12-23.
  • King WA (2008). Chromosome variation in embryos. Cytogenetics and Genome Research 120: 81-90.