University of Guelph ICCI 2011 Cancer Research Symposium

Tuesday May, 3, 9:00 -5:00 Room 1714 OVC LLC

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Register by April 28 to guarantee lunch!

note: poster boards are 47" high x 56" wide

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Keynote Speech 3:30 OVC LLC

Dr. Cheryl London,

Dept. Veterinary Biosciences, College of Veterinary Medicine, The Ohio Sate University

"Targeted Therapy in Veterinary Medicine: the emerging role of tyrosine kinase inhibitors"

Abstract: Advances in molecular biology have permitted the identification of key abnormalities in cancer cells involving proteins that regulate signal transduction, cell survival and cell proliferation. These often involve a class of proteins called tyrosine kinases that phosphorylate and activate other proteins in the cell, regulating a number of cellular processes. Several inhibitors of these kinases (known as tyrosine kinase inhibitors, TKIs) are currently used for the treatment of human cancers. While only two such TKIs are now approved for use in veterinary medicine, early data suggests that they will soon play an important role in the treatment of a variety of canine and feline cancers. Furthermore, data generated from veterinary studies will likely provide important new information regarding how these drugs can be more successfully incorporated into treatment strategies for human cancers, particularly in the setting of microscopic disease.

Brief Bio: Dr. London graduated from Tufts School of Veterinary Medicine in 1990, worked in private practice for 2 years in Maine, then subsequently completed a residency in Medical Oncology at the University of Wisconsin, Madison. She then entered a Ph.D. program in Immunology at Harvard University and after graduating in 1999, was an Assistant Professor of Medical Oncology at UC Davis until 2005. She is now an Associate Professor of Medical Oncology at The Ohio State University College of Veterinary Medicine. Her research interests center primarily around the use of targeted therapeutics in veterinary oncology.

Dr. London is this year's Arthur Willis Distinguished Speaker